A New Line Of Sight
Into Targeted Cancer Therapies

Targeted Alpha-Particle Radiotherapy for Cancer

We are developing a new, proprietary class of personalized alpha-particle radiopharmaceuticals to  transform the treatment landscape of radiotherapies for cancer. Our unique theranostic approach provides the ability to diagnose the tumor and then treat it.

 

Harnessing the Power of Alpha-Particles 

Alpha-particles deliver large amounts of radioactive energy very specifically to tumors, irreparably damaging DNA and reliably killing the targeted tumor cells. We believe the use of alpha-particles provides numerous benefits over currently used beta-particle radiotherapies. Alpha-particles generate more energy and travel a shorter distance compared to beta-particles, making them more cytotoxic, while reducing their effects on healthy tissue.

More Powerful Than Approved
Beta-Particle Therapy

    • Higher atomic mass
    • Lethal double-stranded DNA breaks
    • Cell death assured – NO resistance

Precision Delivery Provides Local Deposition

    • Deposit energy over 3-5 cell radii vs beta particles (up to 200 cells)

Anti-Tumor Immune Response

    • Evidence for antitumor response alone or in combination with immunotherapies

More Powerful Than Approved
Beta-Particle Therapy

    • Higher atomic mass
    • Lethal double-stranded DNA breaks
    • Cell death assured – NO resistance

Precision Delivery Provides Local Deposition

    • Deposit energy over 3-5 cell radii vs beta particles (up to 200 cells)

Anti-Tumor Immune Response

    • Evidence for anti-tumor response alone or in combination with immunotherapies

α-particles are >7,000-fold
greater in atomic mass

 

60,000 lb. Semi

vs 8lb. dumbell